chemistry of bioactive compounds and chemistry of heterocycles, especially heterocyclic derivatives of pyrazoles, thiophenes, thiazoles, pyrimidines, and selenium-containing compounds, their synthesis and modification.
Other areas of my interest are Biochemistry and Pharmaceutical Chemistry, Bioactive Molecules, Fine Organic Synthesis, Multicomponent reactions, Domino reactions, and metal-catalyzed cross-coupling reactions.

1. Y.V. Ostapiuk, O.V. Barabash, M.Y. Ostapiuk, E. Goreshnik, M.D. Obushak, A. Schmidt Thiocyanatoarylation of methyl vinyl ketone under Meerwein conditions for the synthesis of 2-aminothiazole-based heterocyclic systems // Org. Lett. 2022, 24(25), 4575-4579. DOI: 10.1021/acs.orglett.2c01677
2. Y.V. Ostapiuk, M.Y. Ostapiuk, O.V. Barabash, M. Kravets, C. Herzberger, J.C. Namyslo, M.D. Obushak, A. Schmidt One-pot syntheses of substituted 2-aminothiazoles and 2-aminoselenazoles via Meerwein arylation of alkyl vinyl ketones // Synthesis. 2022, 54(16), 3658-3666. DOI: 10.1055/s-0041-1738070
3. Y.V. Ostapiuk, M. Shehedyn, O.V. Barabash, B. Demydchuk, S. Batsyts, C. Herzberger, A. Schmidt Bromoarylation of Methyl 2-Chloroacrylate under Meerwein Conditions for the Synthesis of Substituted 3-Hydroxythiophenes // Synthesis. 2022, 54(03), 732-740. DOI: 10.1055/s-0040-1719849
4. Y. Bazel, V. Sidey, M. Fizer, O. Fedyshyn, V. Vojteková, K. Reiffová, Y. Ostapiuk, O. Tymoshuk Palladium determination with a new dye PNBTAN: Structural, UV-VIS, and DFT study. J. Mol. Struct. 2021, – V. 1246, 131150. Q2
5. N. S. Finiuk, O. Yu. Klyuchivska, I. I. Ivasechko, N. E. Mitina, Yu. V. Ostapiuk, at al. Effect of a novel thiazole derivative and its complex with a polymeric carrier on stability of DNA in human breast cancer cells. Ukr. Biochem. J. 2021; Volume 93, Issue 2, Mar-Apr, pp. 39-51. Q4
6. Finiuk, N.S., Popovych, M.V., Shalai, Y.R., Yu. V. Ostapiuk, et al. Antineoplastic Activity In Vitro of 2-amino-5-benzylthiasol Derivative in the Complex with Nanoscale Polymeric Carriers. Cytol. Genet. 55, 19–27 (2021). Q4
7. V. P. Hreniukh, N. S. Finiuk, Ya. R. Shalai, B. O. Manko, B. V. Manko, Yu. V. Ostapiuk, at al. Effects of thiazole derivatives on intracellular structure and functions in murine lymphoma cells. Ukr. Biochem. J. – 2020; – Vol. 92, Issue 2, – P. 121-130. Q4

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